Acne Vulgaris
How to treat of Ace can see on this link, Skin acne treatment.Acne vulgaris is a disease of the follicles that is multifactorial pilosebaseus involving several types of pathogenesis that includes several issues regarding the sebum, microflora sebaceous follicles, the follicles create keratin process abnormalities, and inflammatory processes.
Lesions on the skin can be, for a closed comedo, open comedo is open, papel, puspel, modulus, cristae, with localization in the region face, chest, back and part of the arm.
Based on existing lesions, made the classification is important to know the outcome of treatment. It also found the influence of factors external factors that can exacerbate acne.
Acne Pathogens
Sebum is mixing of fat consist of cholesterol. Sebum resulted from sebaceous gland as main factor of acne vulgarism, without acne sebum impossible happen. Sebaceous gland stimulated by androgens formed in the skin. The stronger androgen that formed in the goal cel in the sebaceous is dihidrotestosteron (DHT).
from the DHT can change the thickness and quality of keratin permeability in pilosebaceous channels, including the amount and composition of sebum. Skin with acne has been proved can produce 2 – 20 times more DHT than normal skin from the involved area.
Microflora of skin contain of anaerobe germ, anaerobe yeast Pitirosporum and Propionibacterium acnes (P. acnes), P. acne and P. granulosum dominate of face skin. Sebaceous gland very suitable to form colonies on the skin by P. acne and S. epidermidis while puberties, but fatty acid is not the main fed of P. acne. Other component either than lipid of sebaceous gland can be involved.
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